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- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-HBG1/HBG2 antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.6 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Anti-HBG1/HBG2 antibody
Cat. No. JC225246
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-HBG1/HBG2 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human HBG1/HBG2
Reactivity Human
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol HBG1/HBG2
Full name hemoglobin subunit gamma 1/2
Synonyms fetal hemoglobin; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979; TNCY; HBG-T1
Swissprot P69891/P69892
Target Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Anti-HBG1/HBG2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 40-200
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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