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产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul/200ug
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 规格: | 200ug | 产品价格: | ¥5600.0 |
| 产品编号 | bsm-49019M |
| 英文名称 | ANGPTL8 Mouse mAb |
| 中文名称 | 19号染色体开放阅读框80单克隆抗体 |
| 英文别名 | C19orf80; ANGL8_HUMAN; Angiopoietin-like protein 8; betatrophin; Lipasin; Refeeding-induced fat and liver protein; PRO1185; PVPA599; RIFL; TD26; Chromosome 19 open reading frame 80; hepatocellular carcinoma-associated gene TD26; Hepatocellular carcinoma-associated protein TD26. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse) |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant mouse ANGPTL8 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 20 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Interacts with ANGPTL3. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Predominantly expressed in liver. Also expressed in adipose tissues. |
| 翻译后修饰 | Proteolytically cleaved at the N-terminus. |
| 相似性 | Belongs to the ANGPTL8 family. |
| 功能 | Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ANGPTL8 (Angiopoietin Like 8) is a Protein Coding gene. Diseases associated with ANGPTL8 include Breast Angiosarcoma and Breast Sarcoma. Among its related pathways are Lipoprotein metabolism and Metabolism. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Lane 1: Human HepG2 cell lysates
Lane 2: Human MCF-7 cell lysates
Primary: Anti-ANGPTL8 (bsm-49019M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti- Mouse IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 25 kDa
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文献和实验[IF={{ 9.8 }}] {Meiyao Meng. et al. Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner. METABOLISM. 2024 Mar;152:155784} {ELISA} {Mouse}
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