Anti-ST18 antibody

Anti-ST18 antibody

Cat. No.     JC223238
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ST18 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human ST18
Reactivity                 Human, Mouse, Rat
Content                     1.1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 ST18
Full name                 suppression of tumorigenicity 18, zinc finger
Synonyms    NZF3; ZNF387; ZC2HC10
Swissprot    O60284

Target Background
ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells.

Applications
Immunohistochemistry
Predicted cell location: Nucleus and Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 40-150