Product overview Description Anti-ST18 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ST18
Reactivity Human, Mouse, Rat
Content 1.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol ST18
Full name suppression of tumorigenicity 18, zinc finger
Synonyms NZF3; ZNF387; ZC2HC10
Swissprot O60284
Target Background ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells.
Applications Immunohistochemistry
Predicted cell location: Nucleus and Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 40-150