Anti-CYB5R3 antibody

Anti-CYB5R3 antibody

Cat. No.    JC163647 
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CYB5R3 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human CYB5R3
Reactivity                 Human, Mouse, Rat
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-CYB5R3 antibody
Target information
Symbol                 CYB5R3
Full name                 cytochrome b5 reductase 3
Synonyms    B5R; DIA1
Swissprot    P00387

Target Background
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

Anti-CYB5R3 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 20-100    Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 20-100