Product overview
Description Anti-PHLPP1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human PHLPP1
Reactivity Human, Mouse, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-PHLPP1 antibody Target information
Symbol PHLPP1
Full name PH domain and leucine rich repeat protein phosphatase 1
Synonyms PHLPP1
Swissprot O60346
Target Background
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Anti-PHLPP1 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 25-100