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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
7-Acetoxy-4-methylcoumarin
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2747-05-9
- 规格:
100 mg
Product Introduction
Bioactivity
英文名:7-Acetoxy-4-methylcoumarin
描述:7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin, the fluorogenic substrate has been used to study the AchE inhibitor Tacrine·HCl (sc-200172). The compound has also been isolated from Trigonella foenum graceum.

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文献和实验High-Throughput Screening of Peptide Deformylase Inhibitors
. In the third method, f-Met-Lys-7-amino-4-methylcoumarin is used as the substrate. Deformylation by PDF gives an excellent substrate for dipeptidyl peptidase I, which releases the dipeptide Met-Lys and fluorogenic 7-amino-4-methylcoumarin. The combination
RNA Oligonucleotide Synthesis Via 5-Silyl-2-Orthoester Chemistry
from deoxyribonucleic acid (DNA) synthesis strategies, are limited in their ability to produce oligos of sufficient purity and length for high-throughput applications. The more recently developed 5′-silyl-2′-acetoxy ethyl orthoester chemistry (2′-ACE™), circumvents
1Nonradioactive In Situ Hybridization in Atherosclerotic Tissue
, and in vitro transcription. Following hybridization, DIG-probes may be detected with high-affinity specific anti-DIG antibodies (3 ). These antibodies are conjugated with alkaline phosphatase, peroxidase, fluoroscein, rhodamine, AMCA (amino-methylcoumarin
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