Synonyms:AZD-4547
CAS No.:
Molecular Formula:C26H33N5O3
Molecular Weight:463.58
Purity:>99%
Pakage:500mg,1g,2g,5g
Storage:2ºC to 8 ºC, or -20ºC for 2 years
Biological Activity: An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up-regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation and survival.