Anti-CASP8AP2 antibody

Anti-CASP8AP2 antibody

Cat. No.     JC161684     
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CASP8AP2 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human CASP8AP2
Reactivity                 Human, Mouse
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-CASP8AP2 antibody
Target information
Symbol                 CASP8AP2
Full name                 caspase 8 associated protein 2
Synonyms    CED-4; FLASH; RIP25
Swissprot    Q9UKL3

Target Background
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Anti-CASP8AP2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human brain
Recommended dilution: 25-100    Predicted cell location: Cytoplasm and Nucleus
Positive control: Human prostate cancer
Recommended dilution: 25-100