Anti-DEK antibody

Anti-DEK antibody


Cat. No.     JK162790
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-DEK rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human DEK
Reactivity                 Human, Rat
Content                     1.1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 DEK
Full name                 DEK proto-oncogene
Synonyms    D6S231E
Swissprot    P35659

Target Background
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.