Product overview
Description Anti-DEK rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human DEK
Reactivity Human, Rat
Content 1.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-DEK antibody Target information
Symbol DEK
Full name DEK proto-oncogene
Synonyms D6S231E
Swissprot P35659
Target Background
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
Anti-DEK antibody Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human gastric cancer
Recommended dilution: 25-100