Anti-GEMIN2 antibody

Anti-GEMIN2 antibody

Cat. No.    JC160745      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GEMIN2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human GEMIN2
Reactivity                 Human, Mouse, Rat
Content                     0.21 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-GEMIN2 antibody
Target information
Symbol                 GEMIN2
Full name                 gem (nuclear organelle) associated protein 2
Synonyms    SIP1; SIP1-delta
Swissprot    O14893

Target Background
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Anti-GEMIN2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 50-200