Anti-BEX2 antibody

Anti-BEX2 antibody

Cat. No.     JC125564        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-BEX2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human BEX2
Reactivity                 Human
Content                     0.84 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-BEX2 antibody
Target information
Symbol                 BEX2
Full name                 brain expressed X-linked 2
Synonyms    BEX1; DJ79P11.1
Swissprot    Q9BXY8

Target Background
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-BEX2 antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human liver cancer
Recommended dilution: 50-300