Anti-GEMIN2 Polyclonal Antibod

产品简介

英文名称	Anti-GEMIN2 Polyclonal Antibody
宿主	Rabbit
别名	GEMIN2; SIP1; SIP1-delta; gem-associated protein 2
稀释比例	WB 1:5000-8000. IHC 1:50-200.
蛋白分子量	32kDa
Gene ID	8487
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human GEMIN2
亚细胞定位	Cytoplasm Nucleus
Swiss Prot	O14893
背景资料	This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Public Immunogen Range	1-280aa
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with GEMIN2 antibody diluted at 1:6000;Lane: HepG2,Hela,K-562,Jurkat,A431,NIH3T3

Immunohistochemistry?of?paraffin-embedded Human endometrial cancer?with?GEMIN2 antibody diluted at 1:100