Anti-CHRNA10 antibody

Anti-CHRNA10 antibody

Cat. No.     JC160649        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CHRNA10 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human CHRNA10
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-CHRNA10 antibody
Target information
Symbol                 CHRNA10
Full name                 cholinergic receptor, nicotinic, alpha 10 (neuronal)
Synonyms    
Swissprot    Q9GZZ6

Target Background
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma

Anti-CHRNA10 antibody
Applications
Western blotting
Predicted band size:50 kDa
Positive control:A549 cells 
Recommended dilution: 200-1000