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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体名:
Anti-CHRNA10 antibody
- 适应物种:
人/动物/植物
- 浓度:
0.3 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JLC160649
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CHRNA10 rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human CHRNA10
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CHRNA10
Full name cholinergic receptor, nicotinic, alpha 10 (neuronal)
Synonyms
Swissprot Q9GZZ6
Target Background
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
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