Anti-NHP2 antibody

Anti-NHP2 antibody

Cat. No.     JC125589        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-NHP2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human NHP2
Reactivity                 Human, Mouse
Content                     0.18 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-NHP2 antibody
Target information
Symbol                 NHP2
Full name                 NHP2 ribonucleoprotein
Synonyms    DKCB2; NHP2P; NOLA2
Swissprot    Q9NX24

Target Background
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

Anti-NHP2 antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human breast cancer
Recommended dilution: 10-50