Anti-GLI1 antibody

Anti-GLI1 antibody

Cat. No.     JC262900
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GLI1 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human GLI1
Reactivity                 Human, Mouse
Content                     1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 GLI1
Full name                 GLI family zinc finger 1
Synonyms    GLI
Swissprot    P08151

Target Background
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-GLI1 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human gastric cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm and Nucleus
Positive control: Human ovarian cancer
Recommended dilution: 25-100