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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-ERG antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.4 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC220731
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ERG rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human ERG
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ERG
Full name V-ets erythroblastosis virus E26 oncogene homolog (avian)
Synonyms p55; erg-3
Swissprot P11308
Target Background
This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human lung cancer
Recommended dilution: 50-200
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文献和实验为一个复合的电反应。引导的方法是将一个引导电极与角膜接触,将另一个面积较大的参照电极放在额部,当给视网膜以光刺激时,可在示波器上记录到一系列电变化,即视网膜电图。视网膜电图可分成几个部分,一个典型的视网膜电图如附图中的粗线所示。光刺激下,开始有一个小的负波(角膜为负),称 a波,然后出现一个正(角膜为正)的 b波。如刺激强度较大,则在 b波之后,还有一个上升较缓慢的正波(角膜为正),称 c波。在光刺激结束时,还会有一个角膜为正的向上突起,称 d波。据分析, a波主要
a simple ELISA method to detect human anti-antibody response.
Purification Of Anti Peptide Antibody
antibody that could contribute to staining background. The proportion in each pool varies with the peptide immunogen. The quality of the anti-peptide serum seems to increase with multiple boosts - the first bleed may be feeble.











