Anti-CALCOCO1 antibody

Anti-CALCOCO1 antibody

Cat. No.     JC125479        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CALCOCO1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human CALCOCO1
Reactivity                 Human, Mouse, Rat
Content                     0.72 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-CALCOCO1 antibody
Target information
Symbol                 CALCOCO1
Full name                 calcium binding and coiled-coil domain 1
Synonyms    Cocoa; PP13275; calphoglin
Swissprot    Q9P1Z2

Target Background
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3.

Anti-CALCOCO1 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm or Nucleus
Positive control: Human cervical cancer
Recommended dilution: 30-150    Predicted cell location: Cytoplasm or Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 30-150