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- Signalway Antibody
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- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Human TIR domain-containing adapter molecule 1(TICAM1)
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:in vitro E.coli expression system
purification:Greater than 90% as determined by SDS-PAGE.
other_names:Proline-rich, vinculin and TIR domain-containing protein B Putative NF-kappa-B-activating protein 502H Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta
accession_no:Q8IUC6
calculated_mw:76.4 kDa
tag info:NO-tagged
Immunogen Description:Expression Region:1-712aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
产品详细信息请点击：Recombinant Human TIR domain-containing adapter molecule 1(TICAM1)
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文献和实验The large number of cytokines and growth factors implicated in the regulation of liver regeneration has led to the possibility of using these molecules in therapy, namely, in the case of recombinant human hepatocyte growth factor (rhHGF
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
for studying highly controlled biochemical activities, protein?protein interactions, protein?nucleic acid interactions, and protein?small molecule interactions. This unit presents a protocol for constructing functional yeast protein microarrays for global
, where it can be reproduced in large quantities. Examples are plasmids, cosmids, and yeast artificial chromosomes; vectors are often recombinant molecules containing DNA sequences from several sources. cM: See centimorgan. Code: See genetic code . Codon: See genetic
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