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- Signalway Antibody
- USA
- AP78069
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Mouse Toll-like receptor 7(Tlr7),partial
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:Mammalian cell
purification:Greater than 85% as determined by SDS-PAGE.
other_names:
accession_no:P58681
calculated_mw:40.8 kDa
tag info:N-terminal 10xHis-tagged and C-terminal Myc-tagged
Immunogen Description:Expression Region:27-348aa
Sequence Info:Partial
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
产品详细信息请点击：Recombinant Mouse Toll-like receptor 7(Tlr7),partial
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文献和实验Figure 20.12.5 Example of the multisignal ck (s) analysis of a triple protein mixture of a viral glycoprotein (green), its cognate receptor (blue), and a heterogeneous antigen‐recognition receptor fragment
294002 特一行阻断PI3K时，TNFa对IL-8的上调作用消失. 提示负显性突变体的构建是研究信号转导的重要技术手段. 6 参考文献 1 Pierce EA, Liu Q, Igoucheva O, Omarrudin R, Ma H, Diamond SL, Yoon K. Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells. Gene Ther 2003;10:24
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