- 询价
- Signalway Antibody
- USA
- AP78047
- 2026年03月08日
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- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Mouse Pyruvate kinase PKM(Pkm)
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:Baculovirus
purification:Greater than 90% as determined by SDS-PAGE.
other_names:Pyruvate kinase muscle isozyme Pk3,Pkm2, Pykm
accession_no:P52480
calculated_mw:61.8 kDa
tag info:N-terminal 10xHis-tagged and C-terminal Myc-tagged
Immunogen Description:Expression Region:1-531aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation
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文献和实验Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
kinase substrate identification. This approach enables the rapid determination of protein interaction networks in yeast on a proteome?wide level. The same methodology can be readily applied to higher eukaryotic systems with careful consideration
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pyruvate kinase M2-mediated Spi1 lactylation to fuel inflammatory senescence in MASLD 影响因子：52.7 发表期刊：Signal Transduction and Targeted Therapy CUSABIO助力产品： Recombinant Mouse Proto-oncogene Mas (Mas1), partial; CSB-EP013505MO1 研究亮点 代谢相关脂肪性肝病中，髓系Mas受体与PKM
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基因表达，具有双重转录调控功能。下调CDC5L虽增强应激反应但加速细胞死亡，为应激颗粒形成的遗传学基础提供有力证据。 10 靶点：TOLLIP 应用：银屑病的潜在治疗靶点来源：TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2-Mediated Glycolysis in Keratinocytes. Adv Sci (Weinh), 2026 Jul 31 图源：[10] 河北大学闫珍珍博士和吴琛教授
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