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Recombinant Influenza A virus

Polymerase acidic protein(PA),partial
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  • 询价
  • Signalway Antibody已认证
  • USA
  • AP77684
  • 2025年07月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20˚C

    • 英文名

      Recombinant Influenza A virus Polymerase acidic protein(PA),partial

    • 库存

      详询

    • 供应商

      南京莱富赛

    • 规格

      详询

    host_species:Yeast

    purification:Greater than 90% as determined by SDS-PAGE.

    other_names:RNA-directed RNA polymerase subunit P2

    accession_no:A4U6V9

    calculated_mw:26.6 kDa

    tag info:N-terminal 6xHis-tagged

    Immunogen Description:Expression Region:1-209aa
    Sequence Info:Partial

    formulation:Tris-based buffer50% glycerol

    storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
    Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    background:Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.

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