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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-FNDC3B antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
1.8 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC123640
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-FNDC3B rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Full length fusion protein
Reactivity Human, Mouse
Content 1.8 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-FNDC3B antibody
Target information
Symbol FNDC3B
Full name fibronectin type III domain containing 3B
Synonyms FAD104; PRO4979; YVTM2421
Swissprot Q53EP0
Target Background
Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
Anti-FNDC3B antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 30-150 Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 30-150
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