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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-IL17RA antibody
- 宿主:
Rabbit
- 浓度:
1 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC261782
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-IL17RA rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human IL17RA
Reactivity Human
Content 1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IL17RA
Full name interleukin 17 receptor A
Synonyms CD217; IL17R; CANDF5; CDw217; IL-17RA; hIL-17R
Swissprot Q96F46
Target Background
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 100-300
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml261782(IL17RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml261782(IL17RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:96 kDa
Positive control:K562 cells
Recommended dilution: 500-2000
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