Product overview Description Anti-FGF18 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human FGF18 Reactivity Human, Mouse, Rat Content 0.6 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol FGF18 Full name fibroblast growth factor 18 Synonyms ZFGF5; FGF-18 Swissprot O76093
Target Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
Applications Immunohistochemistry Predicted cell location: Cytoplasm Positive control: Human colon cancer Recommended dilution: 50-200 Predicted cell location: Cytoplasm Positive control: Human liver cancer Recommended dilution: 50-200
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml222362(FGF18 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml222362(FGF18 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)