Anti-IKZF3 antibody

Anti-IKZF3 antibody

Cat. No.     JC121936        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-IKZF3 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human IKZF3
Reactivity                 Human, Mouse
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-IKZF3 antibody
Target information
Symbol                 IKZF3
Full name                 IKAROS family zinc finger 3 (Aiolos)
Synonyms    AIO; AIOLOS; ZNFN1A3
Swissprot    Q9UKT9

Target Background
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Anti-IKZF3 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200