Product overview
Description Anti-YARS2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human YARS2
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-YARS2 antibody Target information
Symbol YARS2
Full name tyrosyl-tRNA synthetase 2, mitochondrial
Synonyms TYRRS; CGI-04; MLASA2; MT-TYRRS
Swissprot Q9Y2Z4
Target Background
This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Anti-YARS2 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human lung cancer
Recommended dilution: 50-200