Anti-APLF antibody

Anti-APLF antibody

Cat. No.     JC121653        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-APLF rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human APLF
Reactivity                 Human
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-APLF antibody
Target information
Symbol                 APLF
Full name                 aprataxin and PNKP like factor
Synonyms    APFL; PALF; Xip1; C2orf13
Swissprot    Q8IW19

Target Background
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

Anti-APLF antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200