Anti-DNAJB1 antibody

Anti-DNAJB1 antibody

Cat. No.     JK121744        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-DNAJB1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human DNAJB1
Reactivity                 Human, Mouse
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification


Target information
Symbol                 DNAJB1
Full name                 DnaJ (Hsp40) homolog, subfamily B, member 1
Synonyms    Hdj1; Sis1; HSPF1; Hsp40; RSPH16B
Swissprot    P25685

Target Background
DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene. Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association between HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.