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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体名:
Anti-ANP32E antibody
- 适应物种:
人/动物/植物
- 浓度:
0.5 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JLC161845
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ANP32E rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human ANP32E
Reactivity Human, Mouse, Rat
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ANP32E
Full name acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
Synonyms LANPL; LANP-L
Swissprot Q9BTT0
Target Background
The Anp32 family consists of 32 evolutionarily-conserved proteins and is included within the superfamily of leucine-rich repeat (LRR) proteins. Leucine-rich acidic nuclear protein-like (LANPL), also called ANP32E or Cpd1, is a member of the Anp32 family. LANPL is located in the cytoplasm of peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It has also been detected in the nucleus, cytoplasm and membrane of multiple brain regions. Upon phosphorylation, LANPL colocalizes and inhibits protein phosphatase 2A (PP2A), but does not inhibit PP1. LANPL modulates cell signalling and transduction of gene expression to regulate the morphology and dynamics of the cytoskeleton, cell adhesion, neural development and cerebellar morphogenesis.
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