LGALS1/LGALS1蛋白Recombinant Hum

纯度：

>95% as determined by SDS-PAGE.

基因名：

LGALS1

Uniprot No.：

P09382

别名：

Gal-1, HLBP14, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin

种属：

Homo sapiens (Human)

蛋白长度：

Full Length of Mature Protein

来源：

E.Coli

分子量：

14.6 kDa

表达区域：

2-135aa

氨基酸序列：

ACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD

蛋白标签：

Tag-Free

产品提供形式：

Lyophilized powder

缓冲液：

Lyophilized from a 0.2 µm filtered solution in PBS pH 7.0, 3mM β-Me, 5% Trehalose, 0.02% Tween 20

货期：

5-10 business days

注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

功能：

May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. {ECO:0000269|PubMed:14617626, ECO:0000269|PubMed:18796645, ECO:0000269|PubMed:19497882}.

内毒素：

Less than 1.0 EU/µg as determined by LAL method.

SDS-PAGE:

/

LC-MS Image Description/Western Blot:

/

Product types:

Active Protein & In Stock Protein

Biological_Activity:

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.0-10 ng/ml.

Research Areas:

Cancer

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Reference:

/

Function:

Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.