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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Nuclear receptor subfamily 2 group F member 6 protein (6-194AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
FITC
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P10588
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
/
- 浓度:
>95%,Protein G purified
- 靶点:
NR2F6
- 抗体英文名:
NR2F6 Antibody, FITC conjugated
- 抗体名:
V-erbA-related protein 2 antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5\'-AGGTCA-3\' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验单抗主要是鼠单抗、兔单抗,多抗主要是兔多抗、山羊多抗等,其他种属来源抗体较少。不建议纠结于单抗好还是多抗好,能做出实验的抗体就是好抗体。 在选择上一般建议实验种属和抗体种属亲缘性越远越好,不宜同源。抗体不同种属会要影响接下来二抗的选配。特别是在免疫荧光双标实验中,需要在区别于实验种属的基础上,区分开两个指标的抗体种属来源,以便于二抗区别识别。 3. 关于性价比的选择 抗体的品质高低最终还是需要通过实验结果来呈现的,但是在选择抗体之前我们并无法准确判断抗体的效果
Anti-c-myc-HRP生物素化分子μMACS Streptavidin Kit 免疫沉淀μMACS Protein A MicroBeadsμMACS Protein G MicroBeads 转染细胞MACSelect Kk KitMACSelect 4 KitMACSelect LNGFR KitAnti-Mouse H-2KkCD4-FITCCD271(LNGFR)-FITCMACSelect Control FITC Antibody 凋亡和死亡细胞分选与分析 细胞类别MACS分选产品
cytotoxic cell 抗体依赖细胞毒细胞 ADH antidiuretic hormone 抗利尿激素 AEC 3-amino-9-ethyl-carbazole 3-氨-9-乙基咔唑 AFP alpha(α)-fetal-protein 甲胎蛋白 AHA anti-histone antibody 抗组蛋白抗体 AKP alkaline phosphatase 碱性磷酸酶 ALP Alkaline Phosphatase 碱性
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