- ￥2650
- LSM Bio
- 进口
- PAab05844
- 2025年07月14日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
nuclear receptor subfamily 2, group F, member 6
- 亚型：
IgG2a
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Monoclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Mouse
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
nuclear receptor subfamily 2, group F, member 6
- 抗体英文名：
anti-NR2F6 antibody,NR2F6 antibody
- 抗体名：
anti-NR2F6 抗体,NR2F6 抗体
- 规格：
100μl
NR2F6抗体| NR2F6 antibody
货号 PAab05844
蛋白别名 EAR2 antibody, ERBAL2
蛋白介绍
Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type- specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).
产品描述
anti-NR2F6 antibody is a Mouse Monoclonal antibody againstNR2F6..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab05844(NR2F6 antibody) at dilution of 1:50
Western blot
MCF-7 cells were subjected to SDS PAGE followed by western blot with PAab05844( NR2F6 Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验
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