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- 百奥莱博
- M01022-CEA
- 北京
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
53
- 英文名：
SL327
- CAS号：
305350-87-2
- 保质期：
2年
- 供应商：
北京百奥莱博科技有限公司
- 保存条件：
-20℃，有效期2年，溶入溶剂后-20℃
- 规格：
1mL(10mM)|5mg|10mg|50mg
特别提示：包括MEK-1和MEK-2抑制剂(SL327)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
产品名称：MEK-1和MEK-2抑制剂(SL327)
英文名称：SL327
产品货号：M01022
产品规格：1mL(10mM)|5mg|10mg|50mg
SL-327是可渗透入细胞的MEK-1和MEK-2抑制剂，IC50分别为180nM和220nM。
注：本品仅可用于科研实验，严禁用于临床医疗及其他用途！
CAS号：305350-87-2
纯度：98.0%
分子式：C₁₆H₁₂F₃N₃S
分子量：335.35
结构式：
储存条件：-20℃，有效期2年，溶入溶剂后-20℃请尽量在一个月内使用。
除了MEK-1和MEK-2抑制剂(SL327),，我公司还供应以下相关产品：
| 货号 | 名称 | 规格 |
| YT932 | CENP-E抑制剂(GSK923295) | 10mM×0.2ml|5mg|25mg |
| M00004 | PI3K抑制剂 | 1mL(10mM)|50mg|100mg|200mg|500mg |
| M00676 | p100δ抑制剂(Duvelisib) | 1mL(10mM)|5mg|10mg|50mg|100mg |
| M00702 | TGF-βRI抑制剂(ALK5抑制剂)(SD-208) | 1mL(10mM)|10mg|50mg |
| M00889 | MDMX小分子抑制剂(SJ-172550) | 1mL(10mM)|5mg|10mg|50mg |
| M01303 | 酪氨酸激酶抑制剂(Sulfatinib) | 1mL(10mM)|1mg|5mg|10mg|50mg|100mg |
| M01393 | T24和Caco-2细胞抑制剂(Urolithin A) | 1mL(10mM)|5mg|10mg|25mg|50mg|100mg |
| M01408 | PCA-1/ALKBH3抑制剂(HUHS015) | 1mL(10mM)|1mg|5mg|10mg|50mg|100mg |
| M01415 | 5-HT2A反向激动剂(Nelotanserin) | 1mL(10mM)|1mg|5mg|10mg|50mg|100mg |
| M01423 | type II CDK2抑制剂(K03861) | 1mL(10mM)|2mg|5mg|10mg|25mg|50mg |
| M01618 | VEGFR2抑制剂(Brivanib) | 1mL(10mM)|2mg|5mg|10mg|50mg|100mg |
| M02762 | If抑制剂（Ivabradine hydrochloride） | 1mL(10mM)|10mg|50mg |
| M04464 | SIK2抑制剂(YKL-05-099) | 1mL(10mM)|1mg|5mg|10mg|50mg|100mg |
| M04776 | p38MAPK抑制剂（SKF-86002） | 1mL(10mM)|2mg|5mg|10mg|50mg |
| M05097 | COX-1和COX-2抑制剂(S-(+)-Ketoprofen) | 1mL(10mM)|100mg |
| M05496 | proton pump抑制剂(Bamaquimast) | 1mL(10mM)|5mg|10mg|50mg|100mg |
| M07056 | BRS-3激动剂(MK-5046) | 1mL(10mM)|2mg|5mg|10mg|50mg|100mg |
| M07586 | MDM2抑制剂（NVP-CGM097 stereoisomer） | 1mL(10mM)|2mg|5mg |
| QN0450 | 抑肽酶 | 2mg|5mg |
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文献和实验Deciphering Signaling Pathways In Vivo: The Ras/Raf/Mek/Erk Cascade
The Ras/Raf/MEK/ERK cascade is a highly conserved signal transduction module, whose activation results in a number of different physiological outcomes. Depending on the cell type or the stimulus used, the pathway has been implicated
A Molecular Evolution Approach for Isolation of Intrinsically Active (MEK-Independent) MAP Kinases
Mitogen-activated protein (MAP) kinases are a large family of enzymes composed of about four subfamilies, each containing several isoforms and splicing variants. Many MAP kinases are coexpressed in each eukaryotic cell and coactivated
Raf/MEK/MAPK Signaling Stimulates the Nuclear Translocation and Transactivating Activity of FOXM1
at late-G1 and S phases. Nuclear translocation occurs just before progression into the G2/M phase of the cell cycle and requires activity of the Raf/MEK/MAPK signaling pathway. Using pharmacological modulators, we demonstrated that activity of the Raf/MEK
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