- 询价
- gelatins
- JLC221875
- 上海
- 2025年07月16日
- Rabbit
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- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-ELP2 antibody
- 宿主：
Rabbit
- 浓度：
0.4 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-ELP2 antibody
Cat. No. JLC221875
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ELP2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ELP2
Reactivity Human, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ELP2
Full name elongator acetyltransferase complex subunit 2
Synonyms StIP; StIP1; SHINC-2; STATIP1
Swissprot Q6IA86
Target Background
One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 100-300
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml221875(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml221875(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 2000-10000
Cat. No. JLC221875
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ELP2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ELP2
Reactivity Human, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ELP2
Full name elongator acetyltransferase complex subunit 2
Synonyms StIP; StIP1; SHINC-2; STATIP1
Swissprot Q6IA86
Target Background
One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 100-300
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml221875(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml221875(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 2000-10000
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Anti-ELP2 antibody
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