Product overview
Description Anti-MAP1LC3A rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human MAP1LC3A
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol MAP1LC3A
Full name microtubule-associated protein 1 light chain 3 alpha
Synonyms LC3; LC3A; ATG8E; MAP1ALC3; MAP1BLC3
Swissprot Q9H492
Target Background
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.