- 询价
- 禾午生物
- 国产/进口
- TH0116
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海禾午生物科技有限公司
- 检测方法：
Sandwich ELISA, Double Antibody
- 适应物种：
Human
- 规格：
96T
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文献和实验Gene Amplification of c-erbB-2 Detected by FISH
(4 ) and c-erbB-2 (5 ) located at chromosome band 17q11.2 and encoding a 185,000 Dalton tyrosine kinase (2 ,4 ). Studies conducted on human breast cancers showed 28% to have amplified HER2/neu present (7 ) and it was suggested that amplification or increased
ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment
to small-molecule inhibition with the dual-tyrosine kinase inhibitor lapatinib, and has recently also been implied in oncogenic glutamatergic signaling in melanoma. Mutations involving the ERBB4 gene act as “gain-of-function” mutations and predominantly
Overexpression of erbB- 2 is important in the pathogenesis of a variety of human neoplasms. Overexpression of the erbB- 2 gene product has been associated with poor clinical prognosis with respect to malignancies originating in the ovary
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