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- 详细信息
- 文献和实验
- 技术资料
- 库存:
大量
- 英文名:
Amyloid β Protein Fragment 1-42
- CAS号:
107761-42-2
- 保质期:
2年
- 供应商:
上海瓦兰生物
- 保存条件:
-20°
- 规格:
1MG
性质
| Related Categories | Alzheimer′s Disease, Amyloid Precursor Proteins and Fragments, Amyloid beta Protein Fragments,Neurobiology, Neurodegenerative Disease Peptides, 更多... |
| assay | ≥95% (HPLC) |
| storage temp. | −20°C |
| Gene Information | human ... APP(351) |
产品描述
Amino Acid Sequence
Asp-Ala-Glu-Phe-Arg-His-A
Biochem/physiol Actions
The predominant fragment of amyloid β-protein found in the brains of patients with Alzheimer′s disease and Down′s syndrome.
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文献和实验Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
the deposition of amyloid Aβ peptide. The latter is released from its cognate amyloid precursor protein (APP) by a two-step proteolytic conversion: first, proteolysis of APP by β-secretase, which releases the N-terminus of Aβ, and second, conversion
A detailed understanding of the biochemical events leading to the proteolytic excision of the β-amyloid peptide (A β) from the amyloid precursor protein (APP) has eluded many researchers. This is largely because the measurement of the various APP
Methods for Studying Prion Protein Amyloid
Prion encephalopathies are neurodegenerative diseases characterized by the accumulation of abnormal isoforms of the prion protein (PrP) and the deposition of PrP amyloid in the central nervous systein (CNS) (1 , 2 ) The diseasespecific PrP
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