FITC标记的磷酸化G蛋白信号转导调节因子19抗体

FITC标记的磷酸化G蛋白信号转导调节因子19抗体

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  • ¥2980
  • LMAI Bio
  • LM-5687R-FITC
  • 中国/美国/欧洲
  • 2025年07月12日
  • IF=1:50-200
  • Human, Mouse, Rat,
  • Human, Mouse, Rat,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-5687R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-phospho-RGS19(Ser24)/FITC

    • 抗体名

      Anti-phospho-RGS19(Ser24)/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat,

    • 适应物种

      Human, Mouse, Rat,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的磷酸化G蛋白信号转导调节因子19抗体
    英文名称 Anti-phospho-RGS19(Ser24)/FITC
    中文名称 FITC标记的磷酸化G蛋白信号转导调节因子19抗体
    别    名 RGS19(phospho S24); RGS19(phospho Ser24); G alpha interacting protein; GAIP; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G protein signalling 19; RGSGAIP; RGS19_HUMAN; Regulator of G-protein signaling 19; RGS19; G-alpha-interacting protein.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    产品类型 磷酸化抗体 
    研究领域 肿瘤  免疫学  信号转导  细胞凋亡  转录调节因子  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, 
    产品应用 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 25kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human RGS19 around the phosphorylation site of Ser24 [M(p-S)SH]
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase activating protein that functions to down regulate Galpha i/Galpha q linked signaling.

    Function:
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.

    Subunit:
    Interacts with GIPC PDZ domain.

    Subcellular Location:
    Membrane; Lipid-anchor.

    Tissue Specificity:
    Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.

    Post-translational modifications:
    Fatty acylated. Heavily palmitoylated in the cysteine string motif.
    Phosphorylated, mainly on serine residues.

    Similarity:
    Contains 1 RGS domain.

    Database links:
    UniProtKB/Swiss-Prot: P49795.1

    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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