重组人POLD2(DNA聚合酶δ2)

特别提示：包括重组人POLD2(DNA聚合酶δ2)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人POLD2(DNA聚合酶δ2)
英文名称：Recombinant Human DNA Polymerase Delta Subunit 2
产品货号：JN0978
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Pro469在C端含有His标签。

POLD2质量控制：＞95%(还原性SDS-PAGE)

POLD2制剂：液体

POLD2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于POLD2：
DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3 to 5 exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).

除了重组人POLD2(DNA聚合酶δ2),，我公司还供应以下相关产品：



名称：重组人HDGF(肝癌衍生生长因子)
货号：JN0241
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Met1-Tyr100在C端含有His标签。

HDGF质量控制：＞95%(还原性SDS-PAGE)。

HDGF制剂：冻干品

HDGF保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

HDGF复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于HDGF：
Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.