特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京重组人表皮生长因子受体2(HER2)价格的品牌:百奥莱博,是优质的分子生物学试剂产品,用于科研实验,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人表皮生长因子受体2(HER2)等分子生物学试剂产品请联系我司咨询订购。
名称:北京重组人表皮生长因子受体2(HER2)价格
英文名:Recombinant Human Receptor tyrosine-protein kinase ErbB-2
产地:国产|进口
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Thr23-Thr652在C端含有His标签。
HER2质量控制:>95%(还原性SDS-PAGE)
HER2制剂:冻干品
HER2保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
HER2复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于HER2:
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation. HER2 has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on. HER2 is activated by dimerization and not activated by EGF, TGF-alpha and amphiregulin. Interaction with PTK6 increases its intrinsic kinase activity.It is heterodimer with EGFR, ERBB3 and ERBB4. HER2 associates with the 5-TCAAATTC-3 sequence in the PTGS2/COX-2 promoter and activates its transcription. It implicated in transcriptional activation of CDKN1A and the function of the protein involves STAT3 and SRC. And also it involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.
更多有关北京重组人表皮生长因子受体2(HER2)价格的价格及使用说明等,请联系我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
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北京重组人表皮生长因子受体2(HER2)价格关键词:重组人HER2,JN1595,重组表皮生长因子受体2,重组人表皮生长因子受体2,重组人表皮生长因子受体2蛋白
·重组人精*琥珀酸合成酶(ASS1)
编号:JN0721
英文名称:Recombinant Human Argininosuccinate Synthase
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Lys412在N端含有His标签。
ASS1质量控制:>95%(还原性SDS-PAGE)
ASS1制剂:液体
ASS1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于ASS1:
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.
北京重组人表皮生长因子受体2(HER2)价格关键词:重组人HER2,JN1595,重组表皮生长因子受体2,重组人表皮生长因子受体2,重组人表皮生长因子受体2蛋白
·重组人IL-1R1(IL-1 RI)(C端带Fc标签)
编号:JN1564
英文名称:Recombinant Human Interleukin-1 receptor type 1/IL-1R-1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu18-Thr332在C端带有Fc标签。
IL-1R1/IL-1 RI质量控制:>95%(还原性SDS-PAGE)
IL-1R1/IL-1 RI制剂:冻干品
IL-1R1/IL-1 RI保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IL-1R1/IL-1 RI复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IL-1R1/IL-1 RI:
Interleukin 1 receptor, type I (IL-1R1) is an interleukin receptor that belongs to the interleukin-1 receptor family. IL-1R1 is an 80 kDa transmembrane protein that is expressed predominantly by T cells, fibroblasts, and endothelial cells. This gene along with IL1R2, IL1RL2, and IL1RL1 form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. IL-1R1 is an important mediator involved in many cytokine induced immune and inflammatory responses. It binds to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. The signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. It also binds ligands with comp*(代"a")rable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. An IL1 receptor accessory protein that can heterodimerize with the Type I receptor in the presence of IL1α or IL1β but not IL1ra, was identified. Recombinant IL1 soluble receptor Type I is a potent antagonist of IL1 action.
北京百莱博科技有限公司专业生产供应销*(代"售")生物试剂、化学试剂、抗原抗体、血清血浆、Elisa试剂盒,更多试剂产品需求,欢迎来电咨询选购北京重组人表皮生长因子受体2(HER2)价格。