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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
65373-29-7
- 规格：
10 mM * 1 mL/5 mg/10 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥990.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥562.0 |
| 规格： | 10 mg | 产品价格： | ￥900.0 |
| 规格： | 50 mg | 产品价格： | ￥2700.0 |
| 规格： | 100 mg | 产品价格： | ￥4600.0 |
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MS21570
CAS No. : 65373-29-7
MCE 国际站：MS21570
产品活性：MS21570 是 GPR171 的选择性拮抗剂，其 IC50 值为 220 nM。
研究领域：GPCR/G Protein
作用靶点：GPR171
In Vivo: MS21570 significantly attenuates this CNO-mediated increase in food intake. Interestingly, MS21570 causes a significant increase in center time compared to vehicle suggesting an effect on the anxiety-like behavior. Intra-BLA administration of MS21570 leads to an increase in open arm time on the elevated plus maze although there is no effect on locomotor activity during this test. Interestingly, when administered before and immediately following fear conditioning, MS21570 significantly attenuates freezing measured 24 hours later. Behavioral differences between systemic and intra-BLA administration of MS21570 could be due to the pharmacokinetic and pharmacodynamic properties of the drug. Further studies are needed to characterize the GPR171 antagonist.
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文献和实验In Vitro Opioid Receptor Assays
have internal systems for removing and filling the tissue baths. Four 3‐prong extension clamps to hold stimulating electrode (VWR, cat. no. 21570‐125
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