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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
PACAP [6-38] Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | PACAP [6-38] Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/pacap-%25255B6-38%25255D-peptide |
| 货号: | 350321 |
| 规格: | 1 mg |
| 产品描述: | Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 19-kDa prohormone processed into PACAP-related peptide (PRP-48), PACAP-27 and PACAP-38. PACAP stimulates adenylate cyclase in pituitary cells, playing pivotal roles as neurotransmitter and neuromodulator. PACAP belongs to the glucagon family. |
| 序列: | Human, Ovine, Rat: H-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 or H-FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2 |
| 分子式: | C182H300N56O45S1 |
| 分子量: | 4024.83 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Pituitary adenylate cyclase-activating polypeptide 27; PACAP-27; PACAP27; Pituitary adenylate cyclase-activating polypeptide 38; PACAP-38; PACAP38; ADCYAP1 |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验相关专题 细胞凋亡专题 Vasoactive intestinal peptide (VIP) and the structurally related pituitary adenylate cyclase-activating polypeptide (PACAP), two neuropeptides present in the lymphoid microenvironment, elicit
Specificity Profiling of Protein‐Binding Domains Using One‐Bead‐One‐Compound Peptide Libraries
without the need for any special equipment, and therefore can be employed in any chemical or biochemical laboratory. OBOC peptide libraries have been widely used to map the ligand specificity of proteins, to determine the substrate specificity of enzymes, and to develop inhibitors
腺苷酸环化酶激活肽(PACAP)等神经递质可以引发与脑血管扩张相关的偏头痛发作。在这一背景下,PACAP38已经成为一个关键的信号分子,与偏头痛和丛集性头痛有关。此外,脑成像研究的结果显示,偏头痛患者在输注PACAP38后出现神经和血管改变。一种新的偏头痛特异性药物靶点PACAP38是一种强大的血管扩张剂,是偏头痛发作的有力诱因。与血管活性肠肽(VIP)一起属于胰高血糖素/分泌素超家族。这两种肽都能同样激活VPAC1和VPAC2受体,但只有PACAP38激活了PAC1受体。然而,非常有趣的是,VIP诱导
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