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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
ACTH [1-39] Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | ACTH [1-39] Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/acth-%25255B1-39%25255D |
| 货号: | 350024 |
| 规格: | 1 mg |
| 产品描述: | Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress. ACTH secretion is triggered by the corticotropin-releasing hormone (CRH) released from the hypothalamus, and stimulates the adrenal glands to release corticosteroids such as cortisol. ACTH [1-39] corresponds to full-length ACTH. ACTH [1-24] is conserved across species and is 75% as potent as ACTH. ACTH [1-10] has no ACTH activity but alter blood pressure. ACTH [4-10] has neurological effects. |
| 序列: | Human: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH or H-SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF-OH |
| 分子式: | C207H308N56O58S1 |
| 分子量: | 4541.1 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Adrenocorticotropic hormone; ACTH; corticotropin |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验Functional Identification of Peptide Receptors
. More recently, the dramatic development of genetic engineering has contributed to revealing the structure of complete genes coding for known, as well as novel, biologically active peptides, in addition to a large number of other peptide sequences of unknown
促肾上腺皮质激素(adrenocorticotropichor-mone,ACTH)
垂体前叶分泌的一种激素,能促进皮质激素的产生。其化学成分是39个氨基酸组成的单链多肽,分子量4500道尔顿。不同种属动物ACTH氨基酸组成略有差异。腺垂体中贮存ACTH量很少,人垂体约含ACTH50单位(0.25毫克活性肽),每天分泌1~5单位(5~25微克),紧张情况下分泌量增加。循环中ACTH半衰期短,人约10~25分钟,血浆中ACTH有昼夜规律变化,上午6~8时为高峰,下午6~11时最低。其生理作用为促肾上腺皮质增生,促肾上腺皮质激素合成与释放。糖皮质激素无论是安静
Posttranslational Processing of Peptide Precursors to Fragments
peptides are also capable of converting neural signals into physiological responses, has evoked both interest and doubt. There seem to be about two dozen peptide neurotransmitter candidates and the number is increasing rapidly. Peptides that may serve
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