- ￥600 - 1600
- Abbiotec
- 美国
- 350027
- 2025年12月24日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期：
参照说明书可保存1-2年
- 英文名：
ACTH [18-39] Peptide
- 库存：
一定量库存
- 供应商：
华拓生物
- 规格：
1 mg
| 产品名称： | ACTH [18-39] Peptide |
| 产品链接： | http://www.abbiotec.com/peptides/acth-%25255B18-39%25255D |
| 货号： | 350027 |
| 规格： | 1 mg |
| 产品描述： | Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress. ACTH secretion is triggered by the corticotropin-releasing hormone (CRH) released from the hypothalamus, and stimulates the adrenal glands to release corticosteroids such as cortisol. ACTH [1-39] corresponds to full-length ACTH. ACTH [1-24] is conserved across species and is 75% as potent as ACTH. ACTH [1-10] has no ACTH activity but alter blood pressure. ACTH [4-10] has neurological effects. |
| 序列： | Human: H-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH or H-RPVKVYPNGAEDESAEAFPLEF-OH |
| 分子式： | C112H165N27O36 |
| 分子量： | 2465.72 g/mol |
| 纯度： | Purity > 95% by HPLC |
| 别名： | Adrenocorticotropic hormone; ACTH; corticotropin |
| 形态： | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验are first cleaved with trypsin in water, and subsequently the peptide products are dried and labeled by incubation with trypsin in 18 O-enriched water. One important aspect of this two-step procedure is that peptides, and not proteins, are dried
Functional Identification of Peptide Receptors
. More recently, the dramatic development of genetic engineering has contributed to revealing the structure of complete genes coding for known, as well as novel, biologically active peptides, in addition to a large number of other peptide sequences of unknown
促肾上腺皮质激素（adrenocorticotropichor-mone，ACTH）
垂体前叶分泌的一种激素，能促进皮质激素的产生。其化学成分是39个氨基酸组成的单链多肽，分子量4500道尔顿。不同种属动物ACTH氨基酸组成略有差异。腺垂体中贮存ACTH量很少，人垂体约含ACTH50单位（0.25毫克活性肽），每天分泌1～5单位（5～25微克），紧张情况下分泌量增加。循环中ACTH半衰期短，人约10～25分钟，血浆中ACTH有昼夜规律变化，上午6～8时为高峰，下午6～11时最低。其生理作用为促肾上腺皮质增生，促肾上腺皮质激素合成与释放。糖皮质激素无论是安静
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