CometAssay Single Cell Gel Ele

Single-Cell Gel Electrophoresis (Comet) Assay in Nano-genotoxicology

The Comet assay, or single-cell gel electrophoresis assay, is an easy and simple yet reliable method to evaluate DNA damage in cells. Under the alkaline conditions of this method, DNA strand breaks and alkaline-labile sites are detected

单细胞凝胶电泳分析法（Single Cell Gel Assay）

测定方法，然而，多年来人们所使用的这些测试方法却不能准确与快速的辨识出会使人体致癌的物质。为了解决这些问题，单细胞凝胶电泳法（Single Cell Gel Assay）应运而生，通常亦称之彗星分析法（Comet Assay）。它之所以称为彗星分析法是因为被破坏的DNA形似彗星，此方法已被证实是最具敏感性又最具快速性的方法。研究人员使用这种方法可在24小时内获得初步结果，在十天之内能得到结论性的证据。此种测定方法速度远快于其它方法，不仅可以测出某种物质是否是致癌物，而且还可测出被破坏细胞的损害程度

Single Cell Gel Electrophoresis Assay (Comet Assay) for Evaluating Nanoparticles-Induced DNA Damage in Cells

Comet assay provides a rapid and reliable way to screen genotoxic effects of a wide variety of nanoparticles. Single cell gel electrophoresis assay (SCGE) or comet assay gained in popularity as a standard technique and is widely used