- ¥2570
- peprotech
- 200-36RA
- 美国
- 2025年10月11日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Recombinant Human IL-36RA
- 供应商：
上海研卉生物科技
- 规格：
25ug
Recombinant Human IL-36RA
Product Details
The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36α (IL-1F6), IL-36β (IL-1F8), and IL-36γ (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can induce various activities, including dendritic cell maturation and activation. IL-36RA can antagonize the NF-κB signaling induced by either IL-36α, β or γ by binding to the IL-1Rrp2 receptor in a manner that prevents the initiation of functional signaling. Recombinant Human IL-36RA is an E. coli-derived 17 kDa protein containing 154 amino acid residues.
AA Sequence: VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAGKVIKGEE ISVVPNRWLD ASLSPVILGV QGGSQCLSCG VGQEPTLTLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTVPEADQPV RLTQLPENGG WNAPITDFYF QQCD
Source: E.coli
Synonyms: Interleukin-36RA, FIL1 delta, IL-1F5, IL-1HY1, IL-1L1, IL-1RP3, IL-1ra Homolog 1, IL-1 delta
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Measured by its ability to inhibit secretion of IL-8 by A431 cells in the presence of IL-36γ.
| First Author | Title | Citation | Date | Pubmed |
|---|---|---|---|---|
| Ahsan, F | IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis. | Scientific Reports; 8(1) pg1520 | 24 Jan 2018 | 29367626 Show Usages |
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