相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Recombinant Murine G-CSF
- 供应商:
上海研卉生物科技有限公司
- 库存:
大量
- 规格:
10ug
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Murine G-CSF is a 19.0 kDa protein consisting of 179 amino acid residues.
Source: E.coli
Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFb, pluripoietin
AA Sequence: MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Growth Factors & Cytokines
| First Author | Title | Citation | Date | Pubmed |
|---|---|---|---|---|
| Collins, S J | Multipotent hematopoietic cell lines derived from C/EBPalpha(-/-) knockout mice display granulocyte macrophage-colony-stimulating factor, granulocyte- colony-stimulating factor, and retinoic acid-induced granulocytic differentiation. | Blood; 98(8) pg2382-8 | 15 Oct 2001 | 11588034 Show Usages |
| Gate, L | Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways. | The Journal of Biological Chemistry; 279(10) pg8608-16 | 5 Mar 2004 | 14684749 Show Usages |
| Hadland, B K | A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. | Blood; 104(10) pg3097-105 | 15 Nov 2004 | 15251982 Show Usages |
| Kang, T | Caspase-8 serves both apoptotic and nonapoptotic roles. | Journal of immunology (Baltimore, Md. : 1950); 173(5) pg2976-84 | 1 Sep 2004 | 15322156 Show Usages |
| Testa, U | Impaired myelopoiesis in mice devoid of interferon regulatory factor 1. | Leukemia; 18(11) pg1864-71 | 0 Nov 2004 | 15385939 Show Usages |
| Chan, R J | Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor. | Blood; 105(9) pg3737-42 | 1 May 2005 | 15644411 Show Usages |
| Paling, N R | Tyrosine phosphatase SHP-1 acts at different stages of development to regulate hematopoiesis. | Blood; 105(11) pg4290-7 | 1 Jun 2005 | 15701718 Show Usages |
| Wang, G G | Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus. | Blood; 106(1) pg254-64 | 1 Jul 2005 | 15755900 Show Usages |
| Martin, P | Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes? | Blood; 106(8) pg2871-8 | 15 Oct 2005 | 15998831 Show Usages |
| Haneline, L S | Genetic reduction of class IA PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo. | Blood; 107(4) pg1375-82 | 15 Feb 2006 | 16239435 Show Usages |
| Nishida, S | AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. | Blood; 107(8) pg3303-12 | 15 Apr 2006 | 16380455 Show Usages |
| Patschan, D | Dynamics of mobilization and homing of endothelial progenitor cells after acute renal ischemia: modulation by ischemic preconditioning. | American Journal of Physiology. Renal Physiology; 291(1) pgF176-85 | 0 Jul 2006 | 16478972 Show Usages |
| Smith, D P | MYC levels govern hematopoietic tumor type and latency in transgenic mice. | Blood; 108(2) pg653-61 | 15 Jul 2006 | 16537801 Show Usages |
| Jin, D K | Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. | Nature Medicine; 12(5) pg557-67 | 0 May 2006 | 16648859 Show Usages |
| Dzhagalov, I | The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages. | Blood; 109(4) pg1620-6 | 15 Feb 2007 | 17062731 Show Usages |
| Carter, J H | Early growth response transcriptional regulators are dispensable for macrophage differentiation. | Journal of immunology (Baltimore, Md. : 1950); 178(5) pg3038-47 | 1 Mar 2007 | 17312150 Show Usages |
| Sejas, D P | Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice. | Journal of immunology (Baltimore, Md. : 1950); 178(8) pg5277-87 | 15 Apr 2007 | 17404312 Show Usages |
| Hibbs, M L | Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and granulocytes and mount an inflammatory response in a sterile model of peritonitis. | Journal of immunology (Baltimore, Md. : 1950); 178(10) pg6435-43 | 15 May 2007 | 17475873 Show Usages |
| Munugalavadla, V | Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis. | Blood; 110(5) pg1612-20 | 1 Sep 2007 | 17483298 Show Usages |
| Wang, C | Mouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation. | Blood; 110(10) pg3601-9 | 15 Nov 2007 | 17675553 Show Usages |
| Yang, L | Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis. | Blood; 110(12) pg3853-61 | 1 Dec 2007 | 17702896 Show Usages |
| Wengner, A M | The coordinated action of G-CSF and ELR + CXC chemokines in neutrophil mobilization during acute inflammation. | Blood; 111(1) pg42-9 | 1 Jan 2008 | 17928531 Show Usages |
| Li, J | TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. | The Journal of Clinical Investigation; 117(11) pg3283-95 | 0 Nov 2007 | 17960249 Show Usages |
| Toth, Z E | The combination of granulocyte colony-stimulating factor and stem cell factor significantly increases the number of bone marrow-derived endothelial cells in brains of mice following cerebral ischemia. | Blood; 111(12) pg5544-52 | 15 Jun 2008 | 18268092 Show Usages |
| Jankovic, D | Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia. | Blood; 111(12) pg5672-82 | 15 Jun 2008 | 18388181 Show Usages |
| Schenke-Layland, K | Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. | Stem cells (Dayton, Ohio); 26(6) pg1537-46 | 0 Jun 2008 | 18450826 Show Usages |
| Basile, L A | Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice. | Journal of Translational Medicine; 6 pg26 | 19 May 2008 | 18489769 Show Usages |
| Baek, D | The impact of microRNAs on protein output. | Nature; 455(7209) pg64-71 | 4 Sep 2008 | 18668037 Show Usages |
| Jiang, D | CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages. | Journal of immunology (Baltimore, Md. : 1950); 181(6) pg3923-32 | 15 Sep 2008 | 18768847 Show Usages |
| Eyles, J L | A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis. | Blood; 112(13) pg5193-201 | 15 Dec 2008 | 18824600 Show Usages |
| Gan, B | mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. | Proceedings of the National Academy of Sciences of the United States of America; 105(49) pg19384-9 | 9 Dec 2008 | 19052232 Show Usages |
| Viale, A | Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells. | Nature; 457(7225) pg51-6 | 1 Jan 2009 | 19122635 Show Usages |
| Allen, J D | p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics. | Blood; 113(12) pg2695-705 | 19 Mar 2009 | 19124833 Show Usages |
| Lisak, R P | Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures. | Journal of Neuroinflammation; 6 pg4 | 21 Jan 2009 | 19159481 Show Usages |
| Semerad, C L | E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors. | Proceedings of the National Academy of Sciences of the United States of America; 106(6) pg1930-5 | 10 Feb 2009 | 19181846 Show Usages |
| Velu, C S | Gfi1 regulates miR-21 and miR-196b to control myelopoiesis. | Blood; 113(19) pg4720-8 | 7 May 2009 | 19278956 Show Usages |
| Jeong, M | Thioredoxin-interacting protein regulates hematopoietic stem cell quiescence and mobilization under stress conditions. | Journal of immunology (Baltimore, Md. : 1950); 183(4) pg2495-505 | 15 Aug 2009 | 19625652 Show Usages |
| Sarrazin, S | MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells. | Cell; 138(2) pg300-13 | 23 Jul 2009 | 19632180 Show Usages |
| Kimura, A | The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis. | Blood; 114(21) pg4721-8 | 19 Nov 2009 | 19779039 Show Usages |
| Vemula, S | ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. | Blood; 115(9) pg1785-96 | 4 Mar 2010 | 20008297 Show Usages |
| Stadtfeld, M | A reprogrammable mouse strain from gene-targeted embryonic stem cells. | Nature Methods; 7(1) pg53-5 | 0 Jan 2010 | 20010832 Show Usages |
| Dedhia, P H | Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia. | Blood; 116(8) pg1321-8 | 26 Aug 2010 | 20410507 Show Usages |
| Vemula, S | Essential role for focal adhesion kinase in regulating stress hematopoiesis. | Blood; 116(20) pg4103-15 | 18 Nov 2010 | 20664055 Show Usages |
| Ji, H | Comprehensive methylome map of lineage commitment from haematopoietic progenitors. | Nature; 467(7313) pg338-42 | 16 Sep 2010 | 20720541 Show Usages |
| Kreisel, D | Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis. | The Journal of Clinical Investigation; 121(1) pg265-76 | 0 Jan 2011 | 21157041 Show Usages |
| Richie Ehrlich, L I | In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors. | Blood; 117(9) pg2618-24 | 3 Mar 2011 | 21163922 Show Usages |
| Jiang, D | Regulation of granulocyte and macrophage populations of murine bone marrow cells by G-CSF and CD137 protein. | PLoS ONE; 5(12) pge15565 | 13 Dec 2010 | 21179444 Show Usages |
| Nanua, S | Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane. | Blood; 117(13) pg3539-47 | 31 Mar 2011 | 21285438 Show Usages |
| Popp, M W | Sortase-catalyzed transformations that improve the properties of cytokines. | Proceedings of the National Academy of Sciences of the United States of America; 108(8) pg3169-74 | 22 Feb 2011 | 21297034 Show Usages |
| Stock, A | Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans. | The Journal of Experimental Medicine; 208(4) pg761-73 | 11 Apr 2011 | 21444662 Show Usages |
| Maxwell, M J | Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice. | Journal of immunology (Baltimore, Md. : 1950); 186(12) pg7164-75 | 15 Jun 2011 | 21572033 Show Usages |
| Shang, X | R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization. | The Journal of Biological Chemistry; 286(27) pg24068-78 | 8 Jul 2011 | 21572048 Show Usages |
| Heltemes-Harris, L M | Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia. | The Journal of Experimental Medicine; 208(6) pg1135-49 | 6 Jun 2011 | 21606506 Show Usages |
| Cain, D W | Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism. | PLoS ONE; 6(5) pge19957 | 0 2011 | 21655273 Show Usages |
| Vigne, S | IL-36R ligands are potent regulators of dendritic and T cells. | Blood; 118(22) pg5813-23 | 24 Nov 2011 | 21860022 Show Usages |
| Kreisel, D | Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance. | Blood; 118(23) pg6172-82 | 1 Dec 2011 | 21972291 Show Usages |
| Yamamoto, M | Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development. | PLoS ONE; 6(10) pge25812 | 0 2011 | 22003407 Show Usages |
| Cai, S | Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice. | Bone Marrow Research; 2011 pg252953 | 0 2011 | 22046557 Show Usages |
| Waight, J D | Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism. | PLoS ONE; 6(11) pge27690 | 0 2011 | 22110722 Show Usages |
| de Bruin, A M | IFNγ induces monopoiesis and inhibits neutrophil development during inflammation. | Blood; 119(6) pg1543-54 | 9 Feb 2012 | 22117048 Show Usages |
| Eftychi, C | Myeloid TAKI [corrected] acts as a negative regulator of the LPS response and mediates resistance to endotoxemia. | PLoS ONE; 7(2) pge31550 | 0 2012 | 22348103 Show Usages |
| van Oosten, A L | JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency. | Nature Communications; 3 pg817 | 8 May 2012 | 22569365 Show Usages |
| Ottina, E | Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice. | Blood; 119(25) pg6032-42 | 21 Jun 2012 | 22581448 Show Usages |
| Satpathy, A T | Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. | The Journal of Experimental Medicine; 209(6) pg1135-52 | 4 Jun 2012 | 22615127 Show Usages |
| Schuettpelz, L G | Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function. | Blood; 120(15) pg2981-9 | 11 Oct 2012 | 22936656 Show Usages |
| Xu, L S | Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia. | Journal of immunology (Baltimore, Md. : 1950); 189(7) pg3347-54 | 1 Oct 2012 | 22956576 Show Usages |
| Bian, Z | CD47 deficiency does not impede polymorphonuclear neutrophil transmigration but attenuates granulopoiesis at the postacute stage of colitis. | Journal of immunology (Baltimore, Md. : 1950); 190(1) pg411-7 | 1 Jan 2013 | 23203922 Show Usages |
| Staser, K | Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk. | The Journal of Clinical Investigation; 123(1) pg329-34 | 0 Jan 2013 | 23221339 Show Usages |
| Fossati-Jimack, L | Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells. | PLoS ONE; 8(2) pge57082 | 0 2013 | 23451151 Show Usages |
| Koning, J J | Mesenchymal stem cells are mobilized from the bone marrow during inflammation. | Frontiers in Immunology; 4 pg49 | 0 2013 | 23459632 Show Usages |
| Han, S | Adiponectin deficiency suppresses lymphoma growth in mice by modulating NK cells, CD8 T cells, and myeloid-derived suppressor cells. | Journal of immunology (Baltimore, Md. : 1950); 190(9) pg4877-86 | 1 May 2013 | 23530146 Show Usages |
| Liu, Z | Impaired neutrophil function in 24p3 null mice contributes to enhanced susceptibility to bacterial infections. | Journal of immunology (Baltimore, Md. : 1950); 190(9) pg4692-706 | 1 May 2013 | 23543755 Show Usages |
| Betschinger, J | Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. | Cell; 153(2) pg335-47 | 11 Apr 2013 | 23582324 Show Usages |
| Yan, B | IL-6 cooperates with G-CSF to induce protumor function of neutrophils in bone marrow by enhancing STAT3 activation. | Journal of immunology (Baltimore, Md. : 1950); 190(11) pg5882-93 | 1 Jun 2013 | 23630344 Show Usages |
| Wang, C Q | Runx3 deficiency results in myeloproliferative disorder in aged mice. | Blood; 122(4) pg562-6 | 25 Jul 2013 | 23741011 Show Usages |
| Sonda, N | miR-142-3p prevents macrophage differentiation during cancer-induced myelopoiesis. | Immunity; 38(6) pg1236-49 | 27 Jun 2013 | 23809164 Show Usages |
| Liou, G | Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs. | The Journal of Cell Biology; 202(3) pg563-77 | 5 Aug 2013 | 23918941 Show Usages |
| Pannucci, N L | Loss of the xeroderma pigmentosum group B protein binding site impairs p210 BCR/ABL1 leukemogenic activity. | Blood Cancer Journal; 3 pge135 | 16 Aug 2013 | 23955590 Show Usages |
| Waight, J D | Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis. | The Journal of Clinical Investigation; 123(10) pg4464-78 | 0 Oct 2013 | 24091328 Show Usages |
| Ng, K P | Runx1 deficiency permits granulocyte lineage commitment but impairs subsequent maturation. | Oncogenesis; 2 pge78 | 4 Nov 2013 | 24189977 Show Usages |
| Land, R H | The orphan nuclear receptor NR4A1 specifies a distinct subpopulation of quiescent myeloid-biased long-term HSCs. | Stem cells (Dayton, Ohio); 33(1) pg278-88 | 0 Jan 2015 | 25284014 Show Usages |
| Talabot-Ayer, D | Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice. | Journal of immunology (Baltimore, Md. : 1950); 194(2) pg750-60 | 15 Jan 2015 | 25505285 Show Usages |
| Casbon, A | Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils. | Proceedings of the National Academy of Sciences of the United States of America; 112(6) pgE566-75 | 10 Feb 2015 | 25624500 Show Usages |
| Lawlor, K E | RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. | Nature Communications; 6 pg6282 | 18 Feb 2015 | 25693118 Show Usages |
| Coffelt, S B | IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis. | Nature; 522(7556) pg345-348 | 18 Jun 2015 | 25822788 Show Usages |
| Messmann, J J | In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity. | Blood; 126(9) pg1138-48 | 27 Aug 2015 | 26185131 Show Usages |
| Wang, Y | Uric acid enhances the antitumor immunity of dendritic cell-based vaccine. | Scientific Reports; 5 pg16427 | 10 Nov 2015 | 26553557 Show Usages |
| Hou, Y | High-dose dexamethasone corrects impaired myeloid-derived suppressor cell function via Ets1 in immune thrombocytopenia. | Blood; 127(12) pg1587-97 | 24 Mar 2016 | 26744458 Show Usages |
| Chin, D W | RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity. | Blood Cancer Journal; 6 pge379 | 8 Jan 2016 | 26745853 Show Usages |
| Vasam, G | Impaired Mobilization of Vascular Reparative Bone Marrow Cells in Streptozotocin-Induced Diabetes but not in Leptin Receptor-Deficient db/db Mice. | Scientific Reports; 6 pg26131 | 18 May 2016 | 27188595 Show Usages |
| Malu, K | Cooperative Activity of GABP with PU.1 or C/EBPε Regulates Lamin B Receptor Gene Expression, Implicating Their Roles in Granulocyte Nuclear Maturation. | Journal of immunology (Baltimore, Md. : 1950); 197(3) pg910-22 | 1 Aug 2016 | 27342846 Show Usages |
| Matsumura, K | Peroxiredoxin 1 Contributes to Host Defenses against Mycobacterium tuberculosis. | Journal of immunology (Baltimore, Md. : 1950); 197(8) pg3233-3244 | 15 Oct 2016 | 27605010 Show Usages |
| Niu, S | Broad Infiltration of Macrophages Leads to a Proinflammatory State in Streptozotocin-Induced Hyperglycemic Mice. | Journal of immunology (Baltimore, Md. : 1950); 197(8) pg3293-3301 | 15 Oct 2016 | 27619992 Show Usages |
| Duggan, J M | BCAP inhibits proliferation and differentiation of myeloid progenitors in the steady state and during demand situations. | Blood; 129(11) pg1503-1513 | 16 Mar 2017 | 28087538 Show Usages |
| Netherby, C S | The Granulocyte Progenitor Stage Is a Key Target of IRF8-Mediated Regulation of Myeloid-Derived Suppressor Cell Production. | Journal of immunology (Baltimore, Md. : 1950); 198(10) pg4129-4139 | 15 May 2017 | 28356386 Show Usages |
| Gu, Y | Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma. | Cancer Cell; 32(1) pg115-128.e7 | 10 Jul 2017 | 28697340 Show Usages |
| Karmaus, P W | Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis. | The Journal of Experimental Medicine; 214(9) pg2629-2647 | 4 Sep 2017 | 28784627 Show Usages |
| MacNicol, M C | Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2. | Scientific Reports; 7(1) pg11503 | 14 Sep 2017 | 28912529 Show Usages |
| Riffelmacher, T | Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation. | Immunity; 47(3) pg466-480.e5 | 19 Sep 2017 | 28916263 Show Usages |
| Tusi, B K | Population snapshots predict early haematopoietic and erythroid hierarchies. | Nature; 555(7694) pg54-60 | 1 Mar 2018 | 29466336 Show Usages |
| Durai, V | Altered compensatory cytokine signaling underlies the discrepancy between | The Journal of Experimental Medicine; 215(5) pg1417-1435 | 7 May 2018 | 29572360 Show Usages |
| Tsantikos, E | Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease. | The Journal of Clinical Investigation; 128(6) pg2406-2418 | 1 Jun 2018 | 29708507 Show Usages |
| Nakamura, J | Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease. | Scientific Reports; 8(1) pg7601 | 15 May 2018 | 29765083 Show Usages |
| Jensen, C T | Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis. | The Journal of Experimental Medicine; 215(7) pg1947-1963 | 2 Jul 2018 | 29899037 Show Usages |
| Rodrigues, C F | Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells. | Scientific Reports; 8(1) pg11573 | 1 Aug 2018 | 30069023 Show Usages |
| Teitz-Tennenbaum, S | Autocrine IL-10 Signaling Promotes Dendritic Cell Type-2 Activation and Persistence of Murine Cryptococcal Lung Infection. | Journal of immunology (Baltimore, Md. : 1950); 201(7) pg2004-2015 | 1 Oct 2018 | 30097531 Show Usages |
| Dejani, N N | Intestinal host defense outcome is dictated by PGE | Proceedings of the National Academy of Sciences of the United States of America; 115(36) pgE8469-E8478 | 4 Sep 2018 | 30127026 Show Usages |
| Minzel, W | Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. | Cell; 175(1) pg171-185.e25 | 20 Sep 2018 | 30146162 Show Usages |
| McCarthy, P C | IL-33 regulates cytokine production and neutrophil recruitment via the p38 MAPK-activated kinases MK2/3. | Immunology and Cell Biology; 97(1) pg54-71 | 0 Jan 2019 | 30171775 Show Usages |
| Luo, S | Toxic adjuvants alter the function and phenotype of dendritic cells to initiate adaptive immune responses induced by oral Helicobacter pylori vaccines. | Helicobacter; 23(6) pge12536 | 0 Dec 2018 | 30247802 Show Usages |
| Åhsberg, J | Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner. | The Journal of Biological Chemistry; 288(46) pg33449-61 | 15 Nov 2013 | 24078629 Show Usages |
| Yáñez, A | IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production. | Blood; 125(9) pg1452-9 | 26 Feb 2015 | 25597637 Show Usages |
| Åhsberg, J | Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner. | The Journal of Biological Chemistry; 288(46) pg33449-61 | 15 Nov 2013 | 24078629 Show Usages |
| Yáñez, A | IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production. | Blood; 125(9) pg1452-9 | 26 Feb 2015 | 25597637 Show Usages |
| Denton, A E | Type I interferon induces CXCL13 to support ectopic germinal center formation. | The Journal of Experimental Medicine; 216(3) pg621-637 | 4 Mar 2019 | 30723095 Show Usages |
| Weckbach, L T | Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. | The Journal of Experimental Medicine; 216(2) pg350-368 | 4 Feb 2019 | 30647120 Show Usages |
| Nayak, R | The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. | Nature Communications; 10(1) pg46 | 4 Jan 2019 | 30610188 Show Usages |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Production and Characterization of Recombinant Human and Murine TNF
Here we describe the methods for the expression of human and murine soluble tumor necrosis factor (hTNF and mTNF) in Escherichia coli cells and for their extraction, purification, and characterization. The expression and purification procedure
Technology and Production of Murine Monoclonal and Recombinant Antibodies and Antibody Fragments
MAbs (mAbs) are unique and versatile molecules that have found applications in research, in vitro and in vivo diagnostics, and the treatment of several diseases. Antibody technology has been revolutionized by the hybridoma technology for rnAb
Preparation of Recombinant Retroviruses
Retroviruses are naturally occurring viruses with an RNA genome. A retroviral vector is a modified infectious virus derived from murine or avian species that can be used to introduce nonviral DNAs into a target cell. There are two prominent
技术资料暂无技术资料 索取技术资料








