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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
p21 Cip1 Antibody
- 抗原来源:
Goat,Rabbit,Mouse
- 保质期:
一年
- 库存:
大量
- 适应物种:
人,大鼠,小鼠
- 应用范围:
WB,IHC,IF/ICC,ELISA
- 抗体英文名:
p21 Cip1 Antibody
- 是否单克隆:
多克隆
- 供应商:
上海研卉生物科技有限公司
- 保存条件:
低温
- 宿主:
Rabbit
- 规格:
50ul
名 称:
p21 Cip1 抗体
货 号:
DF6423
来 源:
Rabbit
应 用:
WB,IHC,IF/ICC,ELISA
反 应:
Human, Mouse, Rat
预 测:
Horse(83%), Rabbit(100%), Dog(83%)
蛋白号:
P38936
分子量:
21kDa
浓 度:
1mg/ml
Alternative Names:Expand▼
CAP20; CDK-interacting protein 1; CDKI; CDKN1; Cdkn1a; CDN1A_HUMAN; CIP1; Cyclin Dependent Kinase Inhibitor 1A; Cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1A (P21); Cyclin-dependent kinase inhibitor 1A (p21, Cip1); DNA Synthesis Inhibitor; MDA-6; MDA6; Melanoma differentiation-associated protein 6; Melanoma differentiation-associated protein; p21; P21 protein; p21CIP1; p21Cip1/Waf1; p21WAF; PIC1; SDI1; SLC12A9; WAF1; Wild type p53 activated fragment 1 (WAF1); Wild type p53 activated fragment 1; Wildtype p53-activated fragment 1;
Applications:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
Reactivity:
Human, Mouse, Rat
Predicted Reactivity:
Horse(83%), Rabbit(100%), Dog(83%)
Source:
Rabbit
Clonality:
Polyclonal
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Specificity:
p21 Cip1 Antibody detects endogenous levels of total p21 Cip1.
Format:
Liquid
Concentration:
1mg/ml
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
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文献和实验Analysis of p21CDKN1A Recruitment to DNA Excision Repair Foci in the UV-Induced DNA Damage Response
The cyclin-dependent kinase (CDK) inhibitor p21CDKN1A (also known as p21waf1/cip1 ) is a well known player of the G1 and G2 phase cell cycle checkpoints, which are activated in response to DNA damage. In addition, p21 interacts directly
-induced responses, including a down-regulation of the cyclin-dependent kinase (Cdk2) inhibitors p21CIP1 and p27KIP1 , while attachment to P-L-L did not. We conclude that engagement of the FN-receptor integrin α5β1 induces integrin signaling regulating
Quantification of Cell Cycle-Arresting Proteins
blockage is mainly mediated by the persistent upregulation of one or more cyclin-dependent kinase inhibitors (CKIs), including (though not limited to) p16 INK4A and p21 CIP1 and p27 KIP1 . CKIs operate by binding to cyclin-dependent kinases (CDKs
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